RC1209 Dissolution Tester Technical Specification  

1. Instrument Overview  

- Fully automated dissolution testing system  

- Compliant with global pharmacopeia standards  

- Designed for pharmaceutical quality control and R&D  

2. Testing Principle  

- Precise temperature-controlled vessel system  

- Programmable paddle/basket agitation  

- Automated sampling with filtration  

3. Key Features  

- 8 independent test stations  

- 10.4" color touchscreen interface  

- Integrated peristaltic sampling system  

- Real-time UV monitoring option  

- 21 CFR Part 11 compliant software  

4. Technical Parameters  

- Vessel capacity: 8 x 1000mL  

- Temperature range: 25-45°C (±0.2°C)  

- Rotation speed: 25-250 rpm (±1%)  

- Sampling volume: 1-20mL programmable  

- Power: 110-240V, 50/60Hz  

5. Standards Compliance  

- USP <711> Dissolution  

- EP 2.9.3 Dissolution Test  

- JP 17 Dissolution Test  

- FDA cGMP requirements  

6. Testing Procedure  

1) System Preparation  

- Fill vessels with dissolution medium  

- Load dosage forms  

- Prime sampling lines  

2) Test Programming  

- Set temperature parameters  

- Select rotation method (paddle/basket)  

- Program sampling schedule  

3) Automated Operation  

- Precise medium temperature control  

- Continuous agitation  

- Scheduled sample collection  

7. Performance Metrics  

- Temperature uniformity: ±0.3°C  

- Speed accuracy: ±2 rpm  

- Sampling time precision: ±5 seconds  

- Volume accuracy: ±3%  

8. Applications  

- Immediate-release tablet testing  

- Extended-release formulation development  

- QC batch release testing  

- Method development and validation  

9. Maintenance Requirements  

Daily:  

- Vessel cleaning  

- Tubing inspection  

Weekly:  

- Seal lubrication  

- Pump calibration check  

Monthly:  

- Full system verification  

- Mechanical inspection  

10. Safety Features  

- Over-temperature protection  

- Liquid level sensors  

- Emergency stop function  

- Automatic fault detection  

11. System Advantages  

- Reduced operator variability  

- Improved data integrity  

- Flexible method development  

- Comprehensive audit trail  

12. Customization Options  

- Additional vessel configurations  

- Dissolution-perfusion capabilities  

- Specialized sampling systems  

- Advanced data analysis packages