ADFC1209-12P Dissolution Sampling System Technical Specification  

1. System Overview  

- Automated dissolution sampling system for pharmaceutical testing  

- Designed for USP Apparatus 1 (Basket) and 2 (Paddle) methods  

- 12-position sampling capacity with precise temperature control  

2. Working Principle  

- Programmable peristaltic pump sampling  

- Integrated inline filtration (0.45μm)  

- Temperature-maintained sample collection  

3. Key Features  

- 12 independent sampling channels  

- 10.4" color touchscreen interface  

- Pre-programmed USP/EP methods  

- 21 CFR Part 11 compliant software  

- Real-time temperature monitoring  

4. Technical Parameters  

- Sampling volume: 1-20mL (adjustable)  

- Temperature range: 25-45°C (±0.3°C)  

- Sampling time accuracy: ±5 seconds  

- Flow rate: 5-30mL/min  

- Power: 100-240V AC, 50/60Hz  

5. Standards Compliance  

- USP <711> Dissolution  

- EP 2.9.3 Dissolution Test  

- JP 17 Dissolution Test  

- FDA cGMP requirements  

6. Operation Process  

1) System Preparation  

- Connect to dissolution tester  

- Prime sampling lines  

- Load collection tubes  

2) Method Programming  

- Set sampling time points  

- Program sample volumes  

- Select filtration parameters  

3) Automated Operation  

- Precise timed sampling  

- Maintained sample temperature  

- Automatic line purging  

7. Performance Metrics  

- Volume accuracy: ±2%  

- Carryover: <0.5%  

- Temperature stability: ±0.5°C  

- Filter integrity: >99%  

8. Applications  

- Immediate-release formulation testing  

- QC dissolution testing  

- Method development  

- Stability studies  

9. Maintenance Requirements  

Daily:  

- Replace tubing as needed  

- Clean sample probes  

Weekly:  

- Replace filters  

- Check pump calibration  

Monthly:  

- Full system verification  

10. Safety Features  

- Fluid sensor protection  

- Over-temperature cutoff  

- Emergency stop function  

- Leak detection  

11. System Advantages  

- Reduced operator error  

- Improved reproducibility  

- Automated documentation  

- Flexible method setup  

12. Customization Options  

- Additional collection rack configurations  

- Specialized filtration options  

- Dissolution-perfusion capabilities  

- LIMS integration